Figure 1
From: Cell lineage branching as a strategy for proliferative control
Disturbances and their impact on the dynamics of a two-stage cell lineage. Stem or committed progenitor (CP) cells can self-renew or differentiate to terminally differentiated (TD) cells. The processes of cell division, renewal or differentiation, and cell death can be affected by a number of biologically relevant disturbances that affect the steady state populations of terminal and stem or CP cells.