Fig. 2From: Using mathematical models to understand metabolism, genes, and diseaseHomeostasis of extracellular dopamine. Model simulations of the effect of progressive cell death on the concentration of extracellular dopamine. Black: dopamine concentration declines less than 10 % until more than 80 % of cells have died. White: effect of reducing the activity of the dopamine reuptake transporter (DAT); now the level of extracellular dopamine is very sensitive to the size of the cell population. After [4, 26]Back to article page