Fig. 8From: Regulation of distinct branches of the non-canonical Wnt-signaling network in Xenopus dorsal marginal zone explantsEpistasis experiments. Injection of antisense morpholinos specific for xWnt5a (Wnt5aMo), xWnt11 (Wnt11Mo), pbk (pbkMo), and rab11fip5 (rabMo) impaired convergent extension movements as seen as mild phenotype by a shortened and broad chordin expression or a strong phenotype by a blurred chordin expression or a staining at the borders of the non-closing blastoporus. a Shows representative dorsal marginal zone explants. b Quantification of the epistasis experiments revealed that knock-down of pbk can compensate for the loss of xWnt5a, but (c) knock-down of rab11fip5 cannot compensate for the loss of xWnt11. Shown is the absolute frequency of the indicated phenotypes. The superimposed error bars illustrate the variation between N biological replicates. ** P < 0.01, *** P < 0.001 according to the χ2 test, n: number of analyzed embryosBack to article page