Fig. 2
Faecal bacterial profiles of volunteers with relapsing multiple sclerosis (RMS) infected with Necator americanus (N+) or placebo-treated (PBO). a Relative abundances of bacterial phyla detected in faecal samples collected over the whole course of the WIRMS trial (from Tpre through to Tpost). Percentages in individual pie chart sections indicate the relative proportion of the corresponding phylum. b Differences between the faecal bacterial profiles of N+ and PBO subjects 1 week prior to infection/placebo treatment (Tpre; left), at 1, 5, and 9 months post-infection/placebo treatment (Ttreatment; centre) and 2 months post-anthelmintic treatment (Tpost; right) ordinated by unsupervised principal coordinates analysis (PCoA) at amplicon sequence variant (ASV) level. c PCoA analyses of bacterial profiles of samples collected at individual time points within Ttreatment (i.e. T1, T5 and T9, grey area) from N+ and PBO