Fig. 3
From: NMR structural analysis of the yeast cytochrome c oxidase subunit Cox13 and its interaction with ATP
A comparison of the NMR structure of Cox13 from S. cerevisiae, the cryo-EM structure and the crystal structure of its Bos taurus homologous subunit VIa. a. The cryo-EM structure of the S. cerevisiae III2IV2 supercomplex (PDB ID: 6HU9 [7]). The Complex IV monomers are marked in light gray, the Complex III dimer in dark gray, the Complex IV electron entry site CuA as blue spheres (the size is exaggerated to emphasize the Cu), and Cox13 in orange. b A structural comparison of Cox13 from three different sources. The Cox13 from the III2IV2 S. cerevisiae complex in orange, one of the Cox13 monomers in the NMR (dimer) structure in green, and the B. taurus subunit VIa (from PDB ID: 1occ [9]) in red. On the right, the NMR structure of Cox13 is aligned with the same subunit from the cryo-EM structure. The approximate location of the membrane is marked by dashed lines