Fig. 8
From: Kinesin-3 motors are fine-tuned at the molecular level to endow distinct mechanical outputs
Positively charged lysine resides in the K-loop influence microtubule bending in cells. COS-7 cells were cotransfected with plasmids coding for mCherry-α-tubulin and individual members of constitutively active swap mutants in which the K-loop of each kinesin-3 motors A KIF1A(1-393LZ), B KIF13B(1-412ΔP), and C KIF16B(1–400) were replaced with that of kinesin-1 and D the K-loop of kinesin-1 was replaced with that of KIF1A. Yellow dotted line indicates the cell boundary, and asterisk indicates the nucleus. Scale bars, 10 μm