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Table 2 Total counts of NADPH oxidise (NOX) enzymes identified from genome sequences of 19 metazoan species. Main numbers indicate the total number of unique sequences identified, including isoforms, splice variants and fragmented gene sequences. Superscript numbers indicate the number of additional identical protein sequences (exact sequence variants)

From: Distribution and diversity of ROS-generating enzymes across the animal kingdom, with a focus on sponges (Porifera)

Species

Phylum

Totala

NOX1

NOX2

NOX3

NOX4

NOX5#

Duox

Amphimedon queenslandica

Porifera

6

 

1

  

3 (1)

1

Xestospongia bergquistia

Porifera

3

 

1

  

(1)

1

Tethya wilhelma

Porifera

4

    

2 (1)

1

Ephydatia muelleri

Porifera

5

 

1

  

(1)

3

Oscarella carmela

Porifera

4

 

1

  

1

2

Sycon ciliatum

Porifera

6

 

2

   

4

Mnemiopsis leidyi

Ctenophora

1

    

1

 

Nematostella vectensis

Cnidaria

3

 

2

 

1

  

Capitella teleta

Annelida

5

 

1

  

2

2

Lingula anatina

Brachipoda

12

 

1

 

1

6

4

Drosophila melanogaster

Arthropoda

2

    

1

1

Caenorhabditis elegans

Nematoda

2

     

2

Strongylocentrotus purpuratus

Echinodermata

6

1

1

  

3

1

Acanthaster planci

Echinodermata

8

 

1

  

6

1

Branchiostoma floridae

Chordata

6

 

1

 

1

1

3

Ciona intestinalis

Chordata

8

 

2

 

1

 

5

Danio rerio

Chordata

7

1

1

 

1

1

3

Xenopus tropicalis

Chordata

9

1

11

 

3

1

2

Homo sapiens

Chordata

25

3

1

1

72

6

41

  1. aTotal numbers include gene duplications and fragmented genes
  2. #Presence of DspNOX is included in count for column NOX5 within parenthesis