Fig. 1

Comparison of BBR and sulfasalazine in treating colitis model mice. A Diagram showing the times for DSS and BBR treatment and colorectal sample collection. Colorectal samples were harvested after 7 days of DSS treatment in adult male mice, which were treated with BBR (100 mg/kg) or SASP (200 mg/kg) starting from day 1. B–E The body weights (B), colon length (C), and histological scores (E) were determined and H/E and Alcian Blue staining of rectal sections were performed (D). n=5 per group. Scale bars, 50 μm. Data are presented as means±SEM in B, C, and E. Unpaired two-tailed Student’s t test was applied in B, C, and E. p<0.05 was considered as statistically significant