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Fig. 4 | BMC Biology

Fig. 4

From: The chromosome-level genome and key genes associated with mud-dwelling behavior and adaptations of hypoxia and noxious environments in loach (Misgurnus anguillicaudatus)

Fig. 4

Transcriptome analysis of the drug stress trial and the expression and location of fmo5 in loach Misgurnus anguillicaudatus. a The heatmap of several DGEs (namely, fmo genes, ugt genes, and endoplasmic reticulum stress (RE stress) genes (in red color)) between the control and drug stress group. b The expression profiles of fmo5 genes in livers of wild-type (WT) loach under five drug stress at different time points. c Expression and location of fmo5 gene in the loach. The black dotted box represents the expression signal (liver and intestine tissues) of fmo5 in the loach (top). Immunofluorescence (lower left; liver tissue) and immunohistochemistry (lower right; intestine tissue) of fmo5 in the loach. White and black arrows present the expression signal. H, hepatocyte; GC, goblet cell. Atf6, cyclic AMP-dependent transcription factor 6; ugt1a1, UDP-glucuronosyltransferase 1-1; eif2ak3, eukaryotic translation initiation factor 2-alpha kinase 3; chop, DNA damage-inducible transcript 3 protein; atf4, cyclic AMP-dependent transcription factor 4; Mis0185950.1, Mis0185970.1, Mis0185930.1 (fmo5), dimethylaniline monooxygenase [N-oxide-forming] 5; Mis0072610, Mis0115360.1 (ugt2a1), UDP-glucuronosyltransferase 2A1

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BMC Biology

ISSN: 1741-7007

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