Fig. 6From: Single-cell and spatial transcriptomics reveal changes in cell heterogeneity during progression of human tendinopathyCell–cell crosstalk during tendinopathy progression. A Heatmap depicting the significant interactions among the 22 major cell clusters identified in Fig. 1D. B Heatmap showing the potential ligands send from EC1/Mac and their downstream potential target genes expressed in tenocytes and TSPC. C Heatmap displaying the potential ligand-receptor pairs related to endochondral ossification identified between EC1 and tenocytes and TSPC. D Heatmap showing the potential ligand-receptor pairs associated with endochondral ossification identified between Mac and tenocytes and TSPC. E The bubble plot generated by CellPhoneDB showing potential ligand-receptor pairs associated with angiogenesis between immune cells and EC1. F, G The circo plot showing the potential cytokines and chemokines expressed in immune cells of normal/diseased tendonBack to article page