Fig. 4

Dietary chicory increases Trichuris muris burdens during trickle infection and alters immune responses. A Worm burdens at day 35 after the start of trickle infection in mice fed either a control AIN93G diet or the control diet supplemented with 10% chicory. Mice were infected with 20 eggs at day 0, 7 and 14. n=6-7 mice per group. Shown is mean ± S.E.M. **** p < 0.0001 by T-test. B Principal Component Analysis plots showing clustering of groups based on Fluidigm gene expression analysis. C Mean relative expression of selected genes in caecal tissue D Heat map of gene expression in caecal tissue