Fig. 5

Dietary chicory alters gut microbiota composition during Trichuris muris infection and may inhibit worm expulsion. A Principal Coordinates Analysis plot of caecal microbiota at day 35 after the start of T. muris trickle infection, in mice fed either a control AIN93G diet or the control diet supplemented with 10% chicory Shown is clustering of groups based on 16S rRNA gene amplicon based sequencing (Bray-Curtis Dissimilarity Metrics). B Relative abundance of zOTUs identified as being significantly impacted by diet by ANCOM analysis (followed by Mann-Whitney testing). Shown are median values. n=6 mice per group. ** p < 0.01 by Mann-Whitney test. C Worm burdens at day 21 after a single dose of 300 T. muris eggs in mice fed either the control diet or chicory-supplemented diet. Median values are shown