Fig. 6

Dietary pectin increases Trichuris muris burdens and impairs type-2 immune responses. A Worm burdens at day 35 after the start of trickle infection (median values, pooled from two independent experiments) and B T. muris-specific serum antibody levels (means ± S.E.M.) in mice fed either a control AIN93G diet or the control diet supplemented with 5% pectin. Mice were infected with 20 eggs at day 0, 7 and 14. C Expression (fold changes) of selected genes in caecal tissue (median values), D Worm burdens (median values), E antibody responses (mean ± S.E.M.), and F  gene expression in caecal tissue (median values) in mice 21 days post-infection with 300 T. muris eggs. n= 3-8 mice per group. * p <0.05; ** p<0.01; **p<0.001 0.001 by t-test or Mann-Whitney test