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Fig. 4 | BMC Biology

Fig. 4

From: Nr4a1 marks a distinctive ILC2 activation subset in the mouse inflammatory lung

Fig. 4

SCENIC analysis identifies the regulators in lung ILC2s. a Heatmap shows the main regulons in the C1-C4 subsets respectively. The color key indicates the regulon relative activity. b. Graph showing correlation-based gene regulatory network in 4 ILC2 subsets. The nodes in middle represent the top 4 regulators for each indicated cluster. The around nodes represent genes that are directly targeted by the regulators. Different colors represent different clusters. The size of nodes refers to the weight of genes targeted by the indicated transcription factors. c Graph showing the top 4 regulons in C4 cells. The 4 nodes in the middle represent transcription factors, and the around nodes represent genes targeted by them. Border paint represents different pathways in which genes are involved. The color inside the node indicates different gene expression levels in C4. The color of the edge indicates different transcription factors. d Graph showing correlation-based network of Nr4a1 in ILC2s

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