Fig. 6

Identification of regulons in ILC2s after PD-1 KO. a Heatmap shows the main regulons in Cm4 cells before and after PD-1 KO. The color key indicates the regulon relative activity. b Histograms show the comparison of activities of the Irf2 (74 g), Irf8 (30 g), Usf1 (20 g), and Tfeb_extended (24 g) regulons between PD-1 KO and WT Cm4 cells. Plots show frequency (y-axis) versus area under the curve (AUC; x-axis) for each regulon within the indicated subset. The vertical broken line indicates the average AUC score. c The graph shows the top 4 regulons in PD-1 KO or WT Cm4 cells. d Heatmap shows the main regulons in Cm2 cells before and after PD-1 KO. The color key indicates the regulon relative activity. e The Graph shows the top 4 regulons in PD-1 KO or WT Cm2 cells