Fig. 2

A A schematic of different analytical strategies using machine learning. Each square represents a different dataset, and squares are colored by how they are used to train or test the ML model. B The prediction accuracy, as measured by the AUC, for random forest ML models trained on the vaginal microbiome profiles (genus-level proportion data) in one dataset (rows) and tested in the same or a different dataset (columns). “Ave.” indicates the average AUC of each row (same training dataset) or each column (same testing dataset)