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Fig. 2 | BMC Biology

Fig. 2

From: GADD45A regulates subcutaneous fat deposition and lipid metabolism by interacting with Stat1

Fig. 2

GADD45A is highly expressed in human and mouse subcutaneous WAT. A Heatmap of differentially expressed genes (DEGs) in WAT in mice obesity model (GSE4692, PMID:16733553). B Heatmap of DEGs in BAT and WAT in humans and mice (PMID:30332656). C–F qPCR analysis of BAT-selective (C), pan-selective (D), WAT-selective (E), and Gadd45 family (F) in BAT and iWAT of WT mice (n = 4). G Western blotting for PGC1α, UCP1, and GADD45A in BAT and iWAT of WT mice. The quantification of protein levels was performed densitometrically and normalized to GAPDH levels (n = 4). Error bars represent SEM, *P < 0.05, **P < 0.01, ***P < 0.001, two-tailed Student’s t-test

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