Fig. 1
From: PFTK1 kinase regulates axogenesis during development via RhoA activation
Eip63E deficiency leads to defasciculation and misguidance of VNC axons Ventral views of whole mount stage 14–15 embryos from both Eip63E mutant lines, co-stained for GFP and BP102 (A) or Fasciclin-II (1D4 mAb) (B). Penetrance of VNC defects was calculated as the % of embryos of a given scoring phenotype that show any defect from the total population of such phenotype (GFP + or GFP − embryos). Arrowhead points to normal-looking longitudinal connectives and arrows point to disrupted structures in deficient embryos. L6381 denotes Eip63E81. Scale bar 50 μm