Fig. 2

SRSF2 is required for spermatogenesis. A The testes of Srsf2^cKO were smaller than those of the control (8-week-old, the same as below). B Testis weight of Srsf2^WT and Srsf2^cKO 8-week-old male mice (n = 3). C Testis weight to body weight ratio of Srsf2^WT and Srsf2^cKO 8-week-old male mice (n = 3). Data are presented as the mean ± SEM. P < 0.05(*), 0.01(**) or 0.001(***). D Histological analysis of the caudal epididymes of the Srsf2^WT and Srsf2^cKO mice. (Scale bar: 50 μm) (E) Histological analysis of the seminiferous tubules of the Srsf2^WT and Srsf2.^cKO mice. Scale bar: (top) 100 μm; (bottom) 50 μm. For this part, 3 mice (8-week-old) of each genotype were used for the analysis. Data are presented as the mean ± SEM. P < 0.05(*), 0.01(**) or 0.001(***)