Fig. 7
From: SRSF2 is required for mRNA splicing during spermatogenesis
SRSF2 affects expression and alternative splicing of Stra8, Stag3 and Atr in a direct manner. A Venn diagram shows the correlation among SRSF2-binding genes, DEGs, and AS genes. B The detailed genes of SRSF2-binding, differentially expressed, and AS. C A magnified view showing RNA-seq and LACE-seq signals of the selected candidate genes. IgG, immunoglobulin G. D Quantitative RT-PCR validation of the expression of Stra8, Stag3, and Atr. E Semiquantitative RT-PCR analysis of AS patterns of the changed spliced genes in Srsf2WT and Srsf2cKO testes at P10 (n = 4 per group). PCR primers are listed in Additional file 5: Table S1. The scheme and cumulative data on percentage of the indicated fragments are shown accordingly