Fig. 2

Proportions and magnitudes of positive effect and neutral and negative effect mutations. The plots includes data for \(1.08 \times 10^9\) mutations: \(10^7\) mutations independently drawn using each of the 108 parameters sets (p, n, f, s) sampled in this study. In A, B, grey indicates positive effect mutations, blue indicates neutral mutations and black indicates negative effect mutations. A Stacked histograms indicating the average proportions of mutations drawn using parameter values indicated on the x-axis that have positive, neutral or negative effect. B Mean effect sizes of positive (grey) and negative (black) mutations drawn using parameter values indicated on the x-axes. Boxes indicate data points, lines within boxes indicate the median, whiskers indicate quartiles, and diamonds indicate outliers