Fig. 4

Comparing pangenome and linear aligner performance for short reads. A, B Alignment of short reads with VG giraffe is more memory-efficient (A) and faster (B) when aligning to the minigraph-cactus (MC) pangenome graph compared to the PGGB graph. Linear alignment with minimap2 is the fastest and most memory-efficient. C A larger percentage of all simulated reads is correctly aligned with giraffe regardless of how permissive the minimum map quality filter is