Fig. 3
From: Identification of FtfL as a novel target of berberine in intestinal bacteria
The overall structure of PaFtfL complexed with BBR. A, B The overall structure of PaFtfL-BBR. The four protomers are in different colors. The top dimer is in surface presentation and the bottom dimer is in cartoon presentation. The three types of BBR binding sites are labeled. C The interaction between PaFtfL and BBR in the active site. D The interaction between PaFtfL and BBR in the allosteric site. E Structural comparison among crystal structures of PaFtfL-BBR, PaFtfL-ATP, and MtFtfL-folate (PDB:4JJK)